Granisetron plus dexamethasone for prevention of postoperative nausea and vomiting in patients undergoing laparoscopic surgery: A meta-analysis
نویسندگان
چکیده
Objective This study was designed to compare the effectiveness of granisetron plus dexamethasone for preventing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic surgery. Methods We searched the literature in the Cochrane Library, PubMed, EMBASE, and CNKI. Results In total, 11 randomized controlled trials were enrolled in this analysis. The meta-analysis showed that granisetron in combination with dexamethasone was significantly more effective than granisetron alone in preventing PONV in patients undergoing laparoscopy surgery. No significant differences in adverse reactions (dizziness and headache) were found in association with dexamethasone. Conclusion Granisetron in combination with dexamethasone was significantly more effective than granisetron alone in preventing PONV in patients undergoing laparoscopic surgery, with no difference in adverse reactions between the two groups. Granisetron alone or granisetron plus dexamethasone can be used to prevent PONV in patients undergoing laparoscopic surgery.
منابع مشابه
مقایسهی اثر دوز غیر هوشبر پروپوفول با دگزامتازون بر جلوگیری از تهوع و استفراغ بعد از عمل کله سیستکتومی لاپاراسکوپیک
Background and Objective: Post operative nausea and vomiting (PONV) are unpleasant feelings which frequently occur after laparoscopic cholecystectomy. The aim of this study was to compare the effectiveness of dexamethasone and propofol in prevention of PONV in patients undergoing laparoscopic cholecystectomy. Materials and Methods: 60 patients with ASA status 1-2, who had undergone laparoscopic...
متن کاملPrevention of postoperative nausea and vomiting in patients undergoing laparoscopic bariatric surgery--granisetron alone vs granisetron combined with dexamethasone/droperidol.
BACKGROUND AND OBJECTIVES Laparoscopic bariatric surgeries are associated with an appreciably high rate of postoperative nausea and vomiting. This study was designed to compare the effectiveness of granisetron either alone or in combination with droperidol or dexamethasone, for the prevention of post operative nausea and vomiting (PONV) in patients undergoing laparoscopic bariatric surgeries. ...
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